SCHEMBL9013770

SCHEMBL9013770

C=CCC1(CCC(=O)OCC)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
CYP1A2 P05177 1/20 0.35
TSHR P16473 4/20 0.34
ALDH1A1 P00352 6/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
POLB P06746 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
PTGS2 P35354 1/20 0.33
PDE4D Q08499 1/20 0.33
LMNA P02545 1/20 0.32
TRPA1 O75762 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23484397 0.85 CYP1A2 (0.42) KDM4ECYP1A2TSHRALDH1A1MEN1
SCHEMBL23484497 0.84 CYP1A2 (0.44) KDM4ECYP1A2TSHRALDH1A1MEN1
SCHEMBL5109822 0.80 CYP1A2 (0.44) KDM4ECYP1A2TSHRALDH1A1MEN1
SCHEMBL203062 0.77 ALDH1A1 (0.40) CYP1A2TSHRALDH1A1MEN1KMT2A
SCHEMBL9013508 0.77 DGKA (0.40) KDM4ECYP1A2TSHR
SCHEMBL30569789 0.77 CYP2C19 (0.48) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL1863674 0.76 CYP1A2 (0.47) KDM4ECYP1A2TSHRALDH1A1MEN1
SCHEMBL2048291 0.76 GAA (0.39) KDM4ECYP1A2TSHRALDH1A1KMT2A
SCHEMBL14032871 0.76 CYP1A2 (0.40) KDM4ECYP1A2TSHRALDH1A1MEN1
SCHEMBL28226355 0.75 TSHR (0.55) TSHRALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed