SCHEMBL9013772

SCHEMBL9013772

C=CC[C@H]1CC[C@H](CCCCC2CCC(c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.35
CCR2 P41597 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
USP30 Q70CQ3 1/20 0.33
KDM1A O60341 2/20 0.32
MAOB P27338 1/20 0.32
USP5 P45974 2/20 0.32
HDAC6 Q9UBN7 1/20 0.32
OPRL1 P41146 3/20 0.32
CYP2C9 P11712 2/20 0.31
CNR1 P21554 1/20 0.30
ADRA1A P35348 1/20 0.30
DGAT1 O75907 1/20 0.30
SOAT1 P35610 1/20 0.30
ESR1 P03372 1/20 0.30
CYP3A4 P08684 1/20 0.30
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013765 1.00 ESR2 (0.35) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9512007 0.93 HTR2A (0.37) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9511993 0.93 HTR2A (0.37) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9250171 0.89 USP5 (0.35) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9349609 0.89 USP5 (0.35) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9979962 0.89 USP5 (0.35) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9349604 0.89 USP5 (0.35) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9349590 0.89 USP5 (0.35) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9256820 0.86 CCR2 (0.36) ESR2CCR2HTR2AHTR2CHTR2B
SCHEMBL9256824 0.86 CCR2 (0.36) ESR2CCR2HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP claimed