Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349590 | 1.00 | USP5 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9349604 | 1.00 | USP5 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9979962 | 1.00 | USP5 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9349609 | 1.00 | USP5 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9512007 | 0.95 | HTR2A (0.37) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9511993 | 0.95 | HTR2A (0.37) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL2850582 | 0.95 | CCR2 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL2847709 | 0.92 | HTR2A (0.36) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL2845403 | 0.90 | HTR2A (0.37) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL2850888 | 0.90 | HTR2A (0.37) | USP5HDAC6CCR2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331091-B1 | Cyclohexene derivatives | DAINIPPON INK & CHEMICALS (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5321169-A | Liquid crystals having high nematic to isotropic liquid transition point | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-06-14 | — | — | US | disclosed |
| US-4946986-A | LIQUID CRYSTALS | DAINIPPON INK AND CHEMICALS (JP) | 1990-08-07 | — | — | US | disclosed |