Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012587 | 0.88 | — | — | |
| SCHEMBL6044343 | 0.78 | PTGS2 (0.44) | — | |
| SCHEMBL7848186 | 0.77 | PTGS2 (0.35) | ALOX5APFEN1 | |
| SCHEMBL2653491 | 0.76 | ACLY (0.33) | ALOX5APFEN1CCR2 | |
| SCHEMBL16720034 | 0.75 | PTGS2 (0.39) | — | |
| SCHEMBL16719622 | 0.74 | PTGS2 (0.40) | — | |
| SCHEMBL5790164 | 0.74 | PTGS2 (0.41) | ALOX5APFEN1 | |
| SCHEMBL9118051 | 0.72 | PTGS2 (0.37) | — | |
| SCHEMBL9012696 | 0.72 | HTR2A (0.30) | — | |
| SCHEMBL9013457 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743938-A1 | SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021817-A1 | SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-08-17 | — | — | WO | disclosed |