Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412759 | 0.85 | GPR119 (0.58) | GPR119TGFBR1CHEK2 | |
| SCHEMBL12834985 | 0.85 | GPR119 (0.58) | GPR119CHEK2 | |
| SCHEMBL3591355 | 0.85 | TGFBR1 (0.59) | GPR119TGFBR1CHEK2 | |
| SCHEMBL1769099 | 0.84 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL3256200 | 0.84 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL2456170 | 0.84 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL213773 | 0.84 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL3249170 | 0.84 | KDM4E (0.61) | GPR119CHEK2 | |
| SCHEMBL11956858 | 0.84 | GPR119 (0.64) | GPR119 | |
| SCHEMBL17078731 | 0.83 | GPR119 (0.56) | GPR119CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |