Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.44 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413611 | 0.87 | PIM1 (0.47) | RBP4EPHX2PDE4BKDM4ENPY1R | |
| SCHEMBL2636755 | 0.84 | PDE4B (0.46) | RBP4EPHX2PDE4B | |
| SCHEMBL17738654 | 0.84 | IKBKB (0.42) | IKBKBCHUKNAMPTCACNB4CACNA1A | |
| SCHEMBL15061997 | 0.84 | EPHX2 (0.59) | IKBKBCHUKNAMPTRBP4EPHX2 | |
| SCHEMBL2636756 | 0.83 | SCD (0.45) | RBP4EPHX2KDM4ENPY1RNPY2R | |
| SCHEMBL17559489 | 0.81 | IKBKB (0.51) | IKBKBCHUKNAMPTEPHX2KDM4E | |
| Hydrochloric Acid SCHEMBL9014042 | 0.81 | IKBKB (0.49) | IKBKBCHUKNAMPTPDE4BALDH1A1 | |
| SCHEMBL17955461 | 0.80 | RBP4 (0.67) | IKBKBCHUKNAMPTRBP4CACNB4 | |
| SCHEMBL2091338 | 0.78 | EPHX2 (0.57) | IKBKBCHUKNAMPTEPHX2 | |
| SCHEMBL9014082 | 0.78 | SCD (0.55) | IKBKBCHUKNAMPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |