Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433429 | 0.83 | GABRA1 (0.66) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL10041813 | 0.81 | GABRA1 (0.63) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL168974 | 0.80 | GABRA1 (0.79) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL617923 | 0.80 | GABRA1 (0.61) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL29952629 | 0.80 | GABRA1 (0.61) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL7171833 | 0.77 | KMT2A (0.62) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL6823137 | 0.77 | KMT2A (0.62) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL14433461 | 0.77 | GABRA1 (0.58) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL9013928 | 0.77 | GABRA1 (0.58) | GABRA1GABRB2KMT2AMEN1LMNA | |
| SCHEMBL18657312 | 0.76 | KMT2A (0.62) | GABRA1GABRB2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743937-A1 | BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF | HENKEL CORPORATION (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021152-A1 | BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF | HENKEL CORPORATION (US) | 1995-08-10 | — | — | WO | disclosed |