Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28535972 | 0.92 | EGFR (0.56) | TSHRNAPRTDAOTP53SRD5A2 | |
| SCHEMBL29876739 | 0.89 | HSD17B10 (0.64) | TSHRNAPRTDAOTP53SRD5A2 | |
| SCHEMBL2038730 | 0.89 | HSD17B10 (0.64) | TSHRNAPRTDAOTP53SRD5A2 | |
| 2-Phenylphenol SCHEMBL9013767 | 0.89 | ALDH1A1 (0.71) | TSHRNAPRTDAOTP53SRD5A2 | |
| SCHEMBL6537037 | 0.89 | TTR (0.60) | TSHRNAPRTDAOTP53SRD5A2 | |
| SCHEMBL9067954 | 0.87 | TTR (0.58) | TSHRNAPRTDAOSRD5A2CA12 | |
| Bicarbonate SCHEMBL6431103 | 0.85 | ALDH1A1 (0.62) | TSHRNAPRTCA12CA1CA2 | |
| Terephthalic Acid SCHEMBL9337978 | 0.85 | TSHR (0.72) | TSHRNAPRTDAOTP53SRD5A2 | |
| 2-Phenylphenol SCHEMBL150515 | 0.85 | ALDH1A1 (0.71) | TSHRNAPRTDAOSRD5A2CES2 | |
| 2-Phenylphenol SCHEMBL27898045 | 0.84 | BCL2L1 (0.63) | TSHRNAPRTDAOSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118773756-A | Winding mechanism for preparing polypropylene filaments and method for preparing filaments by using winding mechanism | 扬州市奕轩纤维有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118773756-A | Winding mechanism for preparing polypropylene filaments and method for preparing filaments by using winding mechanism | 扬州市奕轩纤维有限公司 | 2024-10-15 | — | — | CN | disclosed |
| EP-0745233-A1 | CURE CONTROLLED CATALYZED MIXTURES OF EPOXY RESINS AND CURING AGENTS CONTAINING MESOGENIC MOIETIES, B-STAGED AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| WO-1995022079-A1 | CURE CONTROLLED CATALYZED MIXTURES OF EPOXY RESINS AND CURING AGENTS CONTAINING MESOGENIC MOIETIES, B-STAGED AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1995-08-17 | — | — | WO | disclosed |