Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.82 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.72 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9085669 | 0.93 | TBXAS1 (0.84) | PTGIRTBXAS1PTGDRSIGMAR1HTR1A | |
| SCHEMBL9085663 | 0.93 | TBXAS1 (0.84) | PTGIRTBXAS1PTGDRSIGMAR1HTR1A | |
| SCHEMBL9014426 | 0.90 | PTGIR (1.00) | PTGIRTBXAS1PTGDR | |
| SCHEMBL9014199 | 0.85 | PTGIR (0.89) | PTGIRTBXAS1PTGDRHTR1AADRA1D | |
| SCHEMBL9014195 | 0.85 | PTGIR (0.89) | PTGIRTBXAS1PTGDRHTR1AADRA1D | |
| SCHEMBL9014454 | 0.84 | TBXAS1 (1.00) | PTGIRTBXAS1PTGDR | |
| SCHEMBL9014466 | 0.84 | TBXAS1 (1.00) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8411209 | 0.83 | PTGIR (0.56) | PTGIRTBXAS1SIGMAR1 | |
| SCHEMBL8577075 | 0.82 | PTGIR (0.64) | PTGIRTBXAS1SIGMAR1 | |
| SCHEMBL8413684 | 0.81 | PTGIR (0.57) | PTGIRTBXAS1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |