Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.70 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014593 | 1.00 | PTGIR (0.70) | PTGIRTBXAS1PTGDRPTGDR2SIGMAR1 | |
| SCHEMBL9014568 | 0.92 | PTGIR (0.59) | PTGIRTBXAS1PTGDRPTGDR2SIGMAR1 | |
| SCHEMBL9014561 | 0.92 | PTGIR (0.59) | PTGIRTBXAS1PTGDRPTGDR2SIGMAR1 | |
| SCHEMBL9014229 | 0.85 | TBXAS1 (0.77) | PTGIRTBXAS1PTGDR | |
| SCHEMBL9014223 | 0.85 | TBXAS1 (0.77) | PTGIRTBXAS1PTGDR | |
| SCHEMBL9014455 | 0.84 | TBXAS1 (0.79) | PTGIRTBXAS1PTGDRSIGMAR1 | |
| SCHEMBL9014452 | 0.84 | TBXAS1 (0.79) | PTGIRTBXAS1PTGDRSIGMAR1 | |
| SCHEMBL9014617 | 0.84 | PTGIR (0.49) | PTGIRTBXAS1PTGDRPTGDR2 | |
| SCHEMBL9014620 | 0.84 | PTGIR (0.49) | PTGIRTBXAS1PTGDRPTGDR2 | |
| SCHEMBL9014426 | 0.83 | PTGIR (1.00) | PTGIRTBXAS1PTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |