Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890755 | 0.87 | BCL2L1 (0.45) | ADRA2ACYP2D6ADRA2BADRA2CADRA1D | |
| SCHEMBL22829305 | 0.87 | BCL2L1 (0.45) | ADRA2ACYP2D6ADRA2BADRA2CADRA1D | |
| SCHEMBL11815076 | 0.87 | BCL2L1 (0.50) | ADRA2ACYP2D6ADRA2BADRA2CADRA1D | |
| SCHEMBL30173200 | 0.79 | NOTUM (0.44) | ADRA2ACYP2D6ADRA2BADRA2CADRA1D | |
| SCHEMBL11864077 | 0.77 | BCL2L1 (0.34) | ADRA2ACYP2D6ADRA2BADRA2CADRA1D | |
| SCHEMBL739760 | 0.71 | PNMT (0.49) | PNMTDRD2DRD3 | |
| SCHEMBL7126195 | 0.70 | ADRB2 (0.35) | ADRA1A | |
| SCHEMBL7126194 | 0.70 | ADRB2 (0.35) | ADRA1A | |
| SCHEMBL11247615 | 0.69 | — | — | |
| SCHEMBL18297683 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567835-A | Preparation of a vinylsiloxane-benzocylobutene from a hydrolyzable vinylsilane-benzocylobutene | THE DOW CHEMICAL COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| US-5416233-A | Preparation of vinylsilane-benzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |