Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085122 | 0.92 | GRM5 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2888952 | 0.83 | GRM5 (0.33) | GRM5DRD2DRD3PNMT | |
| SCHEMBL4517248 | 0.83 | PIK3CD (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6849836 | 0.82 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7085730 | 0.79 | GRM5 (0.62) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL23501054 | 0.77 | CA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4523627 | 0.77 | CYP1A2 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6650236 | 0.77 | BACE1 (0.35) | BACE1 | |
| SCHEMBL9024457 | 0.77 | BRAF (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9024485 | 0.77 | ALDH2 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416233-A | Preparation of vinylsilane-benzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1995-05-16 | — | — | US | claimed |
| US-4724260-A | Unsaturated alkyl monoarylcyclobutane monomers | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | claimed |
| US-5567835-A | Preparation of a vinylsiloxane-benzocylobutene from a hydrolyzable vinylsilane-benzocylobutene | THE DOW CHEMICAL COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| US-5416233-A | Preparation of vinylsilane-benzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-4783514-A | Polymeric monoarylcyclobutane compositions | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4724260-A | Unsaturated alkyl monoarylcyclobutane monomers | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |