SCHEMBL9014853

SCHEMBL9014853

O=P(Oc1ccccc1)(Oc1ccc(Br)c(Br)c1Br)Oc1ccc(Br)c(Br)c1Br

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.41
HPGD P15428 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA5B Q9Y2D0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505666 1.00 SRC (0.41) SRCHPGDL3MBTL1TDP1CYP3A4
SCHEMBL160182 0.87 TDP1 (0.34) TDP1CYP3A4TSHR
SCHEMBL9507482 0.86 HPGD (0.44) SRCHPGDL3MBTL1TDP1CYP3A4
SCHEMBL29167176 0.80 HPGD (0.47) SRCHPGDL3MBTL1TDP1CYP3A4
SCHEMBL25229878 0.78 TDP1 (0.31) TDP1
SCHEMBL5704272 0.78 MAPK1 (0.46) SRCHPGDL3MBTL1TDP1CYP3A4
SCHEMBL9503632 0.78 MAPK1 (0.46) SRCHPGDL3MBTL1TDP1CYP3A4
SCHEMBL343722 0.77 SRC (0.54) SRCHPGDL3MBTL1TDP1CYP3A4
Triphenyl Phosphate SCHEMBL483692 0.77 SRC (0.64) SRCL3MBTL1TDP1CYP3A4TSHR
Triphenyl Phosphate SCHEMBL18116 0.77 SRC (0.64) SRCL3MBTL1TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3953628-B1 IMPROVED HOOK FOR SUSPENDING CABLES OR HOSE PIPES PENSIOEN B V (NL) 2023-06-07 EP disclosed
US-5556903-A IMPROVED PROCESSABILITY, IMPACT STRENGTH FMC CORPORATION (US) 1996-09-17 US disclosed
EP-0244393-B1 FLAME RETARDANT POLYPHENYLENE ETHER MOLDING COMPOSITIONS FMC Corporation (US) 1993-06-23 EP disclosed
US-4710530-A CONTAINING POLYBROMOTRIPHENYL PHOSPHATES FMC CORPORATION (US) 1987-12-01 US disclosed
EP-0244393-A2 Flame retardant polyphenylene ether molding compositions FMC Corporation (US) 1987-11-04 EP disclosed
EP-0054518-A1 Flame-retardant polymer compositions CIBA-GEIGY AG (CH) 1982-06-23 EP disclosed