Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503411 | 0.89 | INPPL1 (0.38) | HPGDCYP3A4TSHRLMNAMEN1 | |
| SCHEMBL161085 | 0.89 | INPPL1 (0.38) | HPGDCYP3A4TSHRLMNAMEN1 | |
| SCHEMBL30503410 | 0.89 | INPPL1 (0.38) | HPGDCYP3A4TSHRLMNAMEN1 | |
| SCHEMBL29167176 | 0.87 | HPGD (0.47) | HPGDSRCL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9505666 | 0.86 | SRC (0.41) | HPGDSRCL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9014853 | 0.86 | SRC (0.41) | HPGDSRCL3MBTL1TDP1CYP3A4 | |
| SCHEMBL343722 | 0.81 | SRC (0.54) | HPGDSRCL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9622392 | 0.78 | SRC (0.47) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| SCHEMBL2472741 | 0.77 | HTR7 (0.38) | HPGDSRCKDM4ELMNAMEN1 | |
| SCHEMBL29735537 | 0.77 | HTR7 (0.38) | HPGDSRCKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244393-B1 | FLAME RETARDANT POLYPHENYLENE ETHER MOLDING COMPOSITIONS | FMC Corporation (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4710530-A | CONTAINING POLYBROMOTRIPHENYL PHOSPHATES | FMC CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0244393-A2 | Flame retardant polyphenylene ether molding compositions | FMC Corporation (US) | 1987-11-04 | — | — | EP | disclosed |