Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015117 | 0.81 | GCGR (0.50) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL3893630 | 0.78 | AR (0.40) | AHRMEN1HTTKMT2ANOTUM | |
| SCHEMBL17351232 | 0.75 | AHR (0.47) | AHRAKR1C3AKR1C2CYP1B1GYS1 | |
| SCHEMBL8483151 | 0.70 | AHR (0.42) | AHRAKR1C3AKR1C2CYP1B1IKBKB | |
| SCHEMBL3559155 | 0.69 | HPGD (0.64) | MEN1HTTKMT2AKDM4EUSP2 | |
| SCHEMBL9048277 | 0.69 | AHR (0.41) | AHRAKR1C3AKR1C2CYP1B1IKBKB | |
| SCHEMBL9337616 | 0.67 | AR (0.38) | MEN1HTTKMT2ANOTUMKDM4E | |
| SCHEMBL8798565 | 0.67 | KDM4E (0.43) | PIK3CDMEN1HTTKMT2ANOTUM | |
| SCHEMBL8799220 | 0.67 | AHR (0.38) | AHRAKR1C3AKR1C2CYP1B1IKBKB | |
| SCHEMBL10993037 | 0.66 | GCGR (0.45) | MEN1KMT2AUSP2MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |