Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015117 | 0.81 | GCGR (0.50) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL29172448 | 0.80 | GCGR (0.38) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL8662140 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL8664038 | 0.76 | KDM4E (0.34) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL3893100 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL7784864 | 0.75 | MEN1 (0.42) | KDM4EALDH1A1MEN1LMNAHPGD | |
| Bromide SCHEMBL29618239 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL8415325 | 0.75 | MAPK14 (0.56) | KDM4EALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL8663128 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL8662865 | 0.74 | MAPT (0.35) | KDM4EALDH1A1MEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5281719-A | Reacting a methyl N-((trimethylsilyl)methyl)thiobenzimidate with 2,3-dichloro-hexafluorobutene to give a 2-aryl-3,4-bis-(trifluoromethyl)pyrrole and reacting this with a halogenating compound | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5229524-A | Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |