Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015101 | 1.00 | LTB4R (0.52) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 | |
| SCHEMBL8041597 | 1.00 | LTB4R (0.52) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 | |
| SCHEMBL8898032 | 0.84 | CYSLTR1 (0.60) | LTB4RCYSLTR1CYSLTR2 | |
| SCHEMBL8890632 | 0.84 | CYSLTR1 (0.60) | LTB4RCYSLTR1CYSLTR2 | |
| SCHEMBL8889702 | 0.84 | LTB4R (0.63) | LTB4RCYSLTR1CYSLTR2 | |
| SCHEMBL8040414 | 0.80 | USP2 (0.47) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 | |
| SCHEMBL9015096 | 0.80 | USP2 (0.47) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 | |
| SCHEMBL9015087 | 0.80 | USP2 (0.47) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 | |
| SCHEMBL8464080 | 0.78 | LTB4R (0.72) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 | |
| SCHEMBL8464077 | 0.78 | LTB4R (0.72) | LTB4RCYSLTR1USP2CYP3A4CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539128-A | Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline | PFIZER INC. (US) | 1996-07-23 | — | — | US | disclosed |