Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSD | A5PKW4 | 10/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.49 |
| ▸ | GYS1 | P13807 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015058 | 0.95 | PSD (0.43) | PSDABCC8KCNJ11GYS1PKM | |
| SCHEMBL9015077 | 0.90 | ABCC8 (0.47) | PSDABCC8KCNJ11PKMCYP1A2 | |
| SCHEMBL9015124 | 0.90 | PSD (0.40) | PSDABCC8KCNJ11PKMTDP1 | |
| SCHEMBL9015086 | 0.90 | ABCC8 (0.47) | PSDABCC8KCNJ11PKMCYP1A2 | |
| SCHEMBL9015048 | 0.89 | PSD (0.40) | PSDABCC8KCNJ11PKM | |
| SCHEMBL9015094 | 0.87 | PSD (0.52) | PSDABCC8KCNJ11MAPTMEN1 | |
| SCHEMBL9015127 | 0.85 | MAPT (0.40) | PSDABCC8KCNJ11MAPTALDH1A1 | |
| SCHEMBL9015168 | 0.85 | PSD (0.45) | PSDABCC8KCNJ11GYS1MEN1 | |
| SCHEMBL9015076 | 0.85 | PSD (0.44) | PSDABCC8KCNJ11GYS1MEN1 | |
| SCHEMBL9015123 | 0.85 | PSD (0.39) | PSDABCC8KCNJ11PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |