Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 2/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PSD | A5PKW4 | 8/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ARF6 | P62330 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015086 | 1.00 | ABCC8 (0.47) | ABCC8KCNJ11HCRTR1PKMPSD | |
| SCHEMBL9015058 | 0.95 | PSD (0.43) | ABCC8KCNJ11HCRTR1PKMPSD | |
| SCHEMBL9015124 | 0.90 | PSD (0.40) | ABCC8KCNJ11HCRTR1PKMPSD | |
| SCHEMBL9015102 | 0.90 | PSD (0.50) | ABCC8KCNJ11PKMPSDCYP1A2 | |
| SCHEMBL9015048 | 0.89 | PSD (0.40) | ABCC8KCNJ11HCRTR1PKMPSD | |
| SCHEMBL9015094 | 0.87 | PSD (0.52) | ABCC8KCNJ11PSDCNR1KCNQ3 | |
| SCHEMBL9015145 | 0.86 | ARF6 (0.40) | ABCC8KCNJ11HCRTR1PKMPSD | |
| SCHEMBL9015158 | 0.86 | PSD (0.39) | ABCC8KCNJ11HCRTR1PKMPSD | |
| SCHEMBL9015168 | 0.85 | PSD (0.45) | ABCC8KCNJ11PSDCNR1ARF6 | |
| SCHEMBL9015127 | 0.85 | MAPT (0.40) | ABCC8KCNJ11PSDCNR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |