Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 13/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019307 | 0.82 | GPR84 (0.45) | GPR84KMT2AALDH1A1HSD17B10CTSV | |
| SCHEMBL9019271 | 0.76 | HCAR2 (0.47) | GPR84KMT2A | |
| SCHEMBL891281 | 0.76 | GPR84 (0.49) | GPR84KMT2ACTSVCTSLPARP1 | |
| SCHEMBL891164 | 0.74 | GPR84 (0.51) | GPR84KMT2ACTSVCTSLHIF1A | |
| SCHEMBL891065 | 0.74 | GPR84 (0.51) | GPR84KMT2ACTSVCTSLHIF1A | |
| SCHEMBL891178 | 0.74 | GPR84 (0.51) | GPR84KMT2ACTSVCTSLHIF1A | |
| SCHEMBL16416384 | 0.69 | TSHR (0.44) | KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL8450876 | 0.69 | TSHR (0.44) | KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL2609819 | 0.69 | TSHR (0.44) | KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL891076 | 0.69 | DAO (0.44) | GPR84KMT2ACTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |