SCHEMBL891281

SCHEMBL891281

CCCCCc1cc(CCCCC)c(CCCCC)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 13/20 0.49
KMT2A Q03164 1/20 0.47
CTSV O60911 1/20 0.41
CTSL P07711 1/20 0.41
PARP1 P09874 1/20 0.40
HIF1A Q16665 1/20 0.40
EPAS1 Q99814 1/20 0.40
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891164 0.98 GPR84 (0.51) GPR84KMT2ACTSVCTSLHIF1A
SCHEMBL891178 0.98 GPR84 (0.51) GPR84KMT2ACTSVCTSLHIF1A
SCHEMBL891065 0.98 GPR84 (0.51) GPR84KMT2ACTSVCTSLHIF1A
SCHEMBL891076 0.94 DAO (0.44) GPR84KMT2ACTSVCTSLDAO
SCHEMBL2929696 0.87 GPR84 (0.39) GPR84KMT2APARP1
SCHEMBL9015258 0.76 GPR84 (0.45) GPR84KMT2ACTSVCTSLPARP1
SCHEMBL9015231 0.74 PTGS2 (0.35) GPR84KMT2A
SCHEMBL11057529 0.74 HIF1A (0.50) GPR84KMT2AHIF1AEPAS1
SCHEMBL1127503 0.72 SIRT1 (0.39) GPR84KMT2A
SCHEMBL9015135 0.72 GPR84 (0.45) GPR84KMT2ACTSVCTSLPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362278-B2 Methods for the conversion of a substituted furan to a substituted pyrrole CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-01-29 US claimed
US-20120083609-A1 METHODS FOR THE CONVERSION OF A SUBSTITUTED FURAN TO A SUBSTITUTED PYRROLE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-04-05 US claimed
CN-122070352-A Sustainable aviation fuel produced from normal alpha olefin byproducts and method thereof 切弗朗菲利浦化学公司 2026-05-19 CN disclosed
WO-2025054252-A1 SUSTAINABLE JET FUEL AND PROCESS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-03-13 WO disclosed
WO-2025054258-A1 SUSTAINABLE AVIATION FUEL FROM NORMAL ALPHA OLEFIN BYPRODUCTS AND PROCESS FOR SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-03-13 WO disclosed
EP-4359382-A1 TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS Chevron Phillips Chemical Company LP (US) 2024-05-01 EP disclosed
CN-117881658-A Two-step synthesis of pyrrole compounds from furan compounds 切弗朗菲利浦化学公司 2024-04-12 CN disclosed
US-11608317-B2 Two-step synthesis of pyrrole compounds from furan compounds CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2023-03-21 US disclosed
US-20220298109-A1 TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2022-09-22 US disclosed
WO-2022197944-A1 TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-09-22 WO disclosed
US-10435336-B2 Olefin compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-10-08 US disclosed
EP-2791091-A1 PREPARATION OF TRANSITION METAL CARBOXYLATES Chevron Phillips Chemical Company LP (US) 2014-10-22 EP disclosed
WO-2013089963-A1 PREPARATION OF TRANSITION METAL CARBOXYLATES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-06-20 WO disclosed
US-20130150593-A1 ANHYDROUS CHROMIUM(III) HALIDE COMPLEX PREPARATION CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-06-13 US disclosed
US-20130150605-A1 Preparation of Transition Metal Carboxylates CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-06-13 US disclosed
US-8450511-B1 Anhydrous chromium(III) halide complex preparation CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-05-28 US disclosed
US-8362278-B2 Methods for the conversion of a substituted furan to a substituted pyrrole CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-01-29 US disclosed
US-20120083609-A1 METHODS FOR THE CONVERSION OF A SUBSTITUTED FURAN TO A SUBSTITUTED PYRROLE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-04-05 US disclosed
EP-1889617-A1 Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents Freie Universität Berlin (DE) 2008-02-20 EP disclosed
WO-2008006626-A1 TRIPHENYL MODIFIED 5-MEMBERED HETEROCYCLES AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS FREIE UNIVERSITÄT BERLIN (DE) 2008-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083609-A1 METHODS FOR THE CONVERSION OF A SUBSTITUTED FURAN TO A SUBSTITUTED PYRROLE PAH, CPS1, ASNS GPR84 4809/4885KMT2A 2854/4885CTSV 3393/4885
US-20130150593-A1 ANHYDROUS CHROMIUM(III) HALIDE COMPLEX PREPARATION CHD3, WNT3, CBX3 GPR84 3971/4885KMT2A 1706/4885CTSV 1730/4885
US-11608317-B2 Two-step synthesis of pyrrole compounds from furan compounds DDC, DHPS, ACMSD GPR84 4356/4885KMT2A 1762/4885CTSV 3546/4885
US-10435336-B2 Olefin compositions C9, OXER1, ETV1 GPR84 3856/4885KMT2A 2850/4885CTSV 3456/4885
US-20130150605-A1 Preparation of Transition Metal Carboxylates ACMSD, AP1M1, CA1 GPR84 4838/4885KMT2A 1482/4885CTSV 1470/4885
US-20220298109-A1 TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS DDC, DHPS, ACMSD GPR84 4356/4885KMT2A 1762/4885CTSV 3546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.