Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763910 | 0.82 | ADRA1D (0.42) | CHRNA7ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL4716745 | 0.79 | MAPT (0.49) | HTR2AHTR2CHTR1ASLC6A2SLC6A4 | |
| SCHEMBL17583878 | 0.76 | ACACB (0.44) | CHRNA7ACACBHTR2AHTR2CHTR1A | |
| SCHEMBL17912878 | 0.72 | MAPT (0.66) | ADRA1DADRA1AADRA1BHTR1AMAPK1 | |
| SCHEMBL11870778 | 0.71 | SLC6A4 (0.46) | HTR2AHTR2CHTR1ASLC6A2SLC6A4 | |
| SCHEMBL30702565 | 0.71 | HTR2A (0.49) | CHRNA7HTR2AHTR2CHTR1ASLC6A2 | |
| SCHEMBL29144623 | 0.71 | HTR2A (0.49) | CHRNA7HTR2AHTR2CHTR1ASLC6A2 | |
| SCHEMBL13181934 | 0.70 | CYP2C9 (0.40) | ADRA1DADRA1AADRA1BSLC6A2SLC6A4 | |
| SCHEMBL10912774 | 0.70 | SRC (0.41) | ADRA1DADRA1AADRA1BHTR2AHTR2C | |
| SCHEMBL29456016 | 0.70 | KLK5 (0.48) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603322-B1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | OREAL (FR) | 1996-12-11 | — | — | EP | disclosed |
| EP-0603322-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. | OREAL (FR) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993005018-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | L'OREAL (FR) | 1993-03-18 | — | — | WO | disclosed |