Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526302 | 0.90 | TSHR (0.38) | LMNATSHRALDH1A1FGFR4SLC6A2 | |
| SCHEMBL1486026 | 0.81 | GABRR1 (0.43) | LMNATSHRALDH1A1FGFR4GRIK1 | |
| SCHEMBL17335978 | 0.78 | CPB2 (0.44) | LMNATSHRALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL2220364 | 0.76 | GSR (0.50) | LMNATSHRALDH1A1SLC6A2BLM | |
| SCHEMBL3288838 | 0.76 | MEN1 (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL5454196 | 0.75 | TDP1 (0.42) | LMNATSHRSLC6A2SLC6A4BLM | |
| SCHEMBL1890045 | 0.75 | TSHR (0.40) | LMNATSHRALDH1A1SLC6A3 | |
| SCHEMBL14576404 | 0.74 | GSR (0.48) | LMNAALDH1A1SLC6A2BLMSLC6A3 | |
| SCHEMBL17335983 | 0.74 | GSR (0.48) | LMNAALDH1A1SLC6A2BLMSLC6A3 | |
| SCHEMBL17335988 | 0.74 | GSR (0.48) | LMNAALDH1A1SLC6A2BLMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603268-B1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS | BAUSCH & LOMB (US) | 1996-12-18 | — | — | EP | claimed |
| US-5451617-A | Wettable silicone hydrogel compositions and methods for their manufacture | BAUSCH & LOMB INCORPORATED (US) | 1995-09-19 | — | — | US | claimed |
| EP-0603268-B1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS | BAUSCH & LOMB (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5451617-A | Wettable silicone hydrogel compositions and methods for their manufacture | BAUSCH & LOMB INCORPORATED (US) | 1995-09-19 | — | — | US | disclosed |