Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015301 | 0.90 | LMNA (0.36) | TSHRALDH1A1FGFR4LMNASLC6A2 | |
| SCHEMBL3288838 | 0.80 | MEN1 (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL1129429 | 0.76 | — | — | |
| SCHEMBL588667 | 0.76 | — | — | |
| SCHEMBL1486026 | 0.75 | GABRR1 (0.43) | TSHRALDH1A1FGFR4LMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL28726385 | 0.74 | — | — | |
| SCHEMBL5615665 | 0.72 | GRIK1 (0.35) | TSHRALDH1A1FGFR4LMNAMAPK1 | |
| SCHEMBL17335978 | 0.72 | CPB2 (0.44) | TSHRALDH1A1LMNASLC6A2SLC6A4 | |
| SCHEMBL2220364 | 0.71 | GSR (0.50) | TSHRALDH1A1LMNASLC6A2BLM | |
| SCHEMBL17335975 | 0.69 | GSR (0.48) | ALDH1A1LMNASLC6A2BLMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457491-A | Hyperbranched polyamide-amine HPAA and preparation method and application thereof | 华南师范大学 | 2021-03-09 | — | — | CN | disclosed |