Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012641 | 0.69 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL6155919 | 0.68 | KDM4E (0.43) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL23295565 | 0.67 | HTT (0.69) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL23295600 | 0.67 | TLR8 (0.58) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL902311 | 0.66 | PDE5A (0.43) | ALDH1A1HTTMAPTPOLBADORA2A | |
| SCHEMBL30139975 | 0.66 | CFTR (0.82) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL28366027 | 0.66 | CFTR (0.82) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL6553811 | 0.65 | CYP19A1 (0.47) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL29411970 | 0.65 | TP53 (0.89) | ALDH1A1MEN1KMT2AHPGDTP53 | |
| SCHEMBL18152842 | 0.65 | CFTR (0.47) | ALDH1A1MEN1KMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | claimed |
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | disclosed |