Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901537 | 0.66 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBHTTADORA2A | |
| SCHEMBL5175302 | 0.65 | KDM4E (0.50) | ALDH1A1GSK3BGSK3APNPPOLB | |
| SCHEMBL28111190 | 0.65 | CFTR (0.50) | ALDH1A1CFTRMAPK1PDE6DALDH2 | |
| SCHEMBL901534 | 0.65 | ALDH1A1 (0.44) | ALDH1A1CFTRPNPPDE6DALDH2 | |
| SCHEMBL939417 | 0.64 | TNF (0.79) | ALDH1A1MAPTCFTRMAPK1PDE6D | |
| SCHEMBL18152788 | 0.63 | ALDH1A1 (0.61) | ALDH1A1MAPTCFTRPDE6DALDH2 | |
| SCHEMBL5730647 | 0.62 | PDE8B (0.50) | ALDH1A1MAPK1ADORA2A | |
| SCHEMBL28283878 | 0.62 | ADORA2A (0.48) | ALDH1A1MAPTCLK4ADORA2AHSD17B10 | |
| SCHEMBL6981484 | 0.62 | DRD2 (0.58) | ALDH1A1DRD2DRD4DRD3POLB | |
| SCHEMBL18152817 | 0.62 | TNF (0.57) | ALDH1A1MAPTCFTRMAPK1PDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | claimed |
| WO-2012041934-A1 | POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | disclosed |