Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015752 | 0.86 | LMNA (0.53) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015607 | 0.82 | LMNA (0.44) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015746 | 0.81 | LMNA (0.48) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015597 | 0.80 | LMNA (0.45) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015703 | 0.79 | LMNA (0.42) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015588 | 0.77 | GAA (0.54) | LMNAGPR55NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL755528 | 0.77 | GAA (0.59) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL11612164 | 0.77 | LMNA (0.53) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL7943043 | 0.77 | LMNA (0.49) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL6918210 | 0.76 | CA2 (0.59) | LMNARECQLALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516856-A | IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5051531-A | As polymerization catalysts and for crosslinking | ATOCHEM NORTH AMERICA, INC. (US) | 1991-09-24 | — | — | US | disclosed |