Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015644 | 0.96 | LMNA (0.40) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015694 | 0.91 | LMNA (0.39) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015840 | 0.84 | LMNA (0.46) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015646 | 0.82 | LMNA (0.40) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL25639251 | 0.81 | KMT2A (0.48) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL29160406 | 0.80 | CA2 (0.59) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015688 | 0.79 | LMNA (0.34) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9015729 | 0.79 | GAA (0.49) | LMNAHMGCRSMN1; SMN2NPSR1GAA | |
| SCHEMBL9015594 | 0.78 | LMNA (0.41) | LMNARECQLALOX5PTGS1PTGS2 | |
| SCHEMBL9250419 | 0.76 | CA12 (0.42) | LMNACA2CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516856-A | IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-05-14 | — | — | US | disclosed |