Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9171681 | 0.93 | HTR2A (0.48) | HTR2AHTR2CHTR2BSIGMAR1CYP1A2 | |
| SCHEMBL9170094 | 0.91 | HTR2A (0.47) | HTR2AHTR2CHTR2BSIGMAR1CYP1A2 | |
| SCHEMBL9175949 | 0.86 | AKR1C3 (0.46) | HTR2AHTR2CHTR2BSIGMAR1ADRB2 | |
| SCHEMBL9174490 | 0.86 | HTR2A (0.43) | HTR2AHTR2CHTR2BSIGMAR1CASR | |
| SCHEMBL9127416 | 0.80 | HTR2A (0.54) | HTR2AHTR2CHTR2BSIGMAR1CYP1A2 | |
| SCHEMBL10747697 | 0.80 | GRIN2D (0.58) | — | |
| SCHEMBL8465868 | 0.79 | HTR2A (0.67) | HTR2AHTR2CHTR2BSIGMAR1CYP1A2 | |
| SCHEMBL3677922 | 0.79 | HTR2A (0.71) | HTR2AHTR2CHTR2BSIGMAR1CYP1A2 | |
| SCHEMBL2969179 | 0.79 | TAAR1 (0.45) | HTR2AHTR2CHTR2BSIGMAR1CYP2A6 | |
| SCHEMBL9771947 | 0.78 | TAAR1 (0.54) | HTR2ASIGMAR1CYP1A2CYP2A6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516856-A | IMPROVED PROCESS FOR THE MODIFICATION OF THE MOLECULAR CHAIN OF A POLYMER | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5051531-A | As polymerization catalysts and for crosslinking | ATOCHEM NORTH AMERICA, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0344733-A2 | Novel antioxidant-peroxides and their use | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1989-12-06 | — | — | EP | disclosed |