SCHEMBL3677922

SCHEMBL3677922

CC(C)Cc1ccc2ccccc2c1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.71
HTR2C P28335 1/20 0.71
HTR2B P41595 1/20 0.71
CYP1A2 P05177 1/20 0.59
CYP2A6 P11509 1/20 0.59
SIGMAR1 Q99720 3/20 0.53
ADRB2 P07550 2/20 0.48
MC4R P32245 1/20 0.47
MC5R P33032 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
TACR1 P25103 2/20 0.46
BCHE P06276 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11405537 0.94 HTR2A (0.63) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL28292686 0.91 HTR2A (0.57) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL8465868 0.83 HTR2A (0.67) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL268036 0.83 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL17413319 0.83 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL31054190 0.83 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL31054149 0.83 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL10937919 0.83 HTR2A (0.67) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL6301138 0.83 HTR2A (0.67) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL6304187 0.83 HTR2A (0.67) HTR2AHTR2CHTR2BCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504333-A Preparation method and application of 2-methyl-6-alkyl naphthalene 煤炭科学技术研究院有限公司 2025-02-25 CN disclosed
CN-114534787-B Gas-phase dehydrogenation catalyst and method for isopentenol 万华化学集团股份有限公司 2023-12-19 CN disclosed
US-20200030287-A1 PROLINE-BASED NEUROPEPTIDE FF RECEPTOR MODULATORS RESEARCH TRIANGLE INSTITUTE 2020-01-30 US disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-20100087676-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID SAMSUNG PETROCHEMICAL CO., LTD. (KR) 2010-04-08 US disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
EP-1200076-A4 CALCILYTIC COMPOUNDS SMITHKLINE BEECHAM CORP (US) 2005-02-09 EP disclosed
EP-0757985-A1 N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-02-12 EP disclosed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed
EP-0453021-A1 Process for preparing a cycloalkanone and/or cycloalkanol DSM N.V. (NL) 1991-10-23 EP disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed
US-4154715-A Polymeric polyblend compositions toughened by addition of liquid polymers of a conjugated diene monomer MONSANTO COMPANY (US) 1979-05-15 US disclosed
US-4049732-A Continuous telomerization process and its liquid products LITHIUM CORPORATION OF AMERICA (US) 1977-09-20 US disclosed
US-4041088-A Recirculation telomerization process and its liquid telomers and liquid telomers produced thereby LITHIUM CORPORATION OF AMERICA (US) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 HTR2A 4120/4885HTR2C 2910/4885HTR2B 3791/4885
US-20200030287-A1 PROLINE-BASED NEUROPEPTIDE FF RECEPTOR MODULATORS NPFFR1, NPFFR2, NPBWR1 HTR2A 356/4885HTR2C 419/4885HTR2B 462/4885
US-20100087676-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID DDC, HAO2, AOC1 HTR2A 4288/4885HTR2C 4721/4885HTR2B 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.