SCHEMBL8465868

SCHEMBL8465868

CC(O)Cc1ccc2ccccc2c1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.67
HTR2C P28335 1/20 0.67
HTR2B P41595 1/20 0.67
CYP1A2 P05177 2/20 0.55
CYP2A6 P11509 1/20 0.55
ADRB2 P07550 2/20 0.52
UGT2B7 P16662 1/20 0.52
SIGMAR1 Q99720 3/20 0.50
MME P08473 2/20 0.46
ACE P12821 2/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
MEN1 O00255 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
KMT2A Q03164 1/20 0.45
HIF1A Q16665 1/20 0.45
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9176689 0.92 HTR2A (0.53) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL6843917 0.90 HTR2A (0.52) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL9176391 0.85 HTR2A (0.49) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL3677922 0.83 HTR2A (0.71) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL9126649 0.82 HTR2A (0.46) HTR2AHTR2CHTR2BCYP1A2ADRB2
SCHEMBL5562898 0.81 THRB (0.47) HTR2AHTR2CHTR2BADRB2MEN1
SCHEMBL2482277 0.81 HTR2A (0.53) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL14756856 0.81 HTR2A (0.44) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL2482281 0.81 HTR2A (0.58) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL10500945 0.81 HTR2A (0.62) HTR2AHTR2CHTR2BCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61293936-A None JP disclosed
CN-113651308-A Azalea leaf derived carbon material and preparation method and application thereof 浙江工业大学 2021-11-16 CN disclosed
CN-111675599-A Method for catalyzing and oxidizing aromatic benzyl tertiary C-H bond into tertiary alcohol by metalloporphyrin 浙江工业大学 2020-09-18 CN disclosed
US-9989853-B2 2018-06-05 US disclosed
US-20160291472-A1 HARDMASK COMPOSITION AND METHOD OF FORMING PATTERN USING THE HARDMASK COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-06 US disclosed
US-20160282721-A1 HARDMASK COMPOSITION AND METHOD OF FORMING PATTERN USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-09-29 US disclosed
US-9359276-B2 Monomer for hardmask composition, hardmask composition including monomer, and pattern forming method using hardmask composition CHEIL INDUSTRIES, INC. (KR) 2016-06-07 US disclosed
US-20160011511-A1 HARDMASK COMPOSITION AND METHOD OF FORMING PATTERN USING THE HARDMASK COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-14 US disclosed
US-20160005625-A1 Hardmask composition and method of forming pattern using the hardmask composition SAMSUNG ELECTRONICS CO LTD (KR) 2016-01-07 US disclosed
US-20150008212-A1 MONOMER FOR HARDMASK COMPOSITION, HARDMASK COMPOSITION INCLUDING MONOMER, AND PATTERN FORMING METHOD USING HARDMASK COMPOSITION CHEIL INDUSTRIES, INC. (KR) 2015-01-08 US disclosed
US-5990357-A CATALYTIC OXIDATION OF ISOALKYLAROMATIC HYDROCARBONS INTO KETONES, ALCOHOLS AND PEROXIDES; THESE PRODUCTS ARE VALUABLE INTERMEDIATE PRODUCTS FOR ORGANIC SYNTHESES RUTGERS KUREHA SOLVENTS GMBH (DE) 1999-11-23 US disclosed
US-5422038-A Ferroelectric liquid crystal material with sufficient spontaneous polarization, high speed response capability, wide temperature range SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-06 US disclosed
EP-0416946-B1 Optically active naphthalene derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL CO (JP) 1994-11-09 EP disclosed
EP-0416946-A2 Optically active naphthalene derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-13 EP disclosed
JP-S61293936-A LIQUID-PHASE DEHYDRATION OF ALCOHOL HAVING AROMATIC SIDE-CHAIN AT ALPHA-SITE KUREHA CHEM IND CO LTD 1986-12-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150008212-A1 MONOMER FOR HARDMASK COMPOSITION, HARDMASK COMPOSITION INCLUDING MONOMER, AND PATTERN FORMING METHOD USING HARDMASK COMPOSITION DDRGK1, MINK1, DNM1 HTR2A 4423/4885HTR2C 4347/4885HTR2B 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.