Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.59 |
| ▸ | TYMS | P04818 | 3/20 | 0.47 |
| ▸ | TK1 | P04183 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | POLD1 | P28340 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749986 | 0.93 | RNASE1 (0.68) | RNASE1TYMSTK1TK2 | |
| SCHEMBL21489369 | 0.88 | RNASE1 (0.50) | RNASE1TYMSTK1POLBTK2 | |
| Ammonia Solution, Strong SCHEMBL10491034 | 0.88 | RNASE1 (0.49) | RNASE1TYMSTK1POLBTK2 | |
| SCHEMBL25374598 | 0.87 | POLB (0.61) | RNASE1TYMSTK1POLBPOLA1 | |
| SCHEMBL9015805 | 0.86 | RNASE1 (0.59) | RNASE1TYMSTK1TK2 | |
| SCHEMBL23045153 | 0.86 | RNASE1 (0.57) | RNASE1TYMSTK1TK2 | |
| SCHEMBL5531135 | 0.85 | RNASE1 (0.56) | RNASE1TYMSTK1TK2 | |
| SCHEMBL5531136 | 0.85 | RNASE1 (0.56) | RNASE1TYMSTK1TK2 | |
| SCHEMBL2379935 | 0.85 | RNASE1 (0.56) | RNASE1TYMSTK1TK2 | |
| SCHEMBL10486964 | 0.85 | RNASE1 (0.45) | RNASE1TYMSTK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519126-A | COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1996-05-21 | — | — | US | disclosed |