Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylamine SCHEMBL1685095 | 0.94 | — | — | |
| Tert-Butylamine SCHEMBL28161497 | 0.88 | — | — | |
| Tert-Butylamine SCHEMBL28670024 | 0.88 | — | — | |
| Tert-Butylamine SCHEMBL5736553 | 0.87 | — | — | |
| Tert-Butylamine SCHEMBL6064515 | 0.87 | FDPS (0.33) | — | |
| Tert-Butylamine SCHEMBL8051 | 0.87 | — | — | |
| Tert-Butylamine SCHEMBL4706460 | 0.82 | ALDH1A1 (0.36) | — | |
| Tert-Butylamine SCHEMBL13270275 | 0.82 | ALDH1A1 (0.33) | — | |
| Tert-Butylamine SCHEMBL263850 | 0.80 | — | — | |
| Tert-Butylamine SCHEMBL184405 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108546269-A | The method that clavulanic acid tert-butylamine salt is recycled from crystalline mother solution | 国药集团威奇达药业有限公司 | 2018-09-18 | — | — | CN | claimed |
| WO-2024005240-A1 | INSULIN RECEPTOR-BINDING APTAMER DIMER AND USE THEREOF | 포항공과대학교 산학협력단 | 2024-01-04 | — | — | WO | disclosed |
| CN-111808152-B | Deacylation method of sucralose-6-acetate | 山东新和成精化科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111808152-A | Deacylation method of sucralose-6-acetate | 山东新和成精化科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-108546269-A | The method that clavulanic acid tert-butylamine salt is recycled from crystalline mother solution | 国药集团威奇达药业有限公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-103333170-B | Benzimidazoles compound and application thereof | 清华大学 | 2016-08-10 | — | — | CN | disclosed |
| EP-3044334-A1 | PDGF AND VEGF APTAMERS HAVING IMPROVED STABILITY AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED DISEASES AND DISORDERS | Somalogic, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015035305-A1 | PDGF AND VEGF APTAMERS HAVING IMPROVED STABILITY AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED DISEASES AND DISORDERS | SOMALOGIC, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| US-5519126-A | COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0406309-A4 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | — | 1992-08-19 | — | — | EP | disclosed |
| EP-0406309-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4973679-A | Process for oligonucleo tide synthesis using phosphormidite intermediates | UNIVERSITY PATENTS, INC. (US) | 1990-11-27 | — | — | US | disclosed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |
| US-4668777-A | POLYNUCLEOTIDE INTERMEDIATES | UNIVERSITY PATENTS, INC. (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0061746-B1 | PHOSPHORAMIDITE COMPOUNDS AND THEIR USE IN PRODUCING OLIGONUCLEOTIDES | UNIVERSITY PATENTS, INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4500707-A | Nucleosides useful in the preparation of polynucleotides | UNIVERSITY PATENTS, INC. (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0061746-A1 | Phosphoramidite compounds and their use in producing oligonucleotides | UNIVERSITY PATENTS, INC. (US) | 1982-10-06 | — | — | EP | disclosed |
| US-3981828-A | ISOCYANATE TRIMERIZATION CATALYSTS | BASF WYANDOTTE CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |