Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21286973 | 0.91 | NPC1 (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9122570 | 0.91 | TSHR (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2381790 | 0.88 | THRB (0.44) | TYMPTSHRLMNAKDM4ETHRB | |
| SCHEMBL9015796 | 0.88 | THRB (0.44) | TYMPTSHRLMNAKDM4ETHRB | |
| SCHEMBL9122864 | 0.82 | NPC1 (0.38) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL21286970 | 0.82 | HTT (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9015839 | 0.80 | KDM4E (0.32) | HPGDTYMPKDM4ENOS2 | |
| SCHEMBL4633204 | 0.79 | NPC1 (0.48) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8010899 | 0.78 | ALOX5 (0.43) | LMNAKDM4E | |
| SCHEMBL23239690 | 0.75 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385721-A | X-ray radiology and computer tomography; uniform coating of the soft tissues; medical diagnosis | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | claimed |
| EP-0609589-A2 | Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | claimed |
| EP-0609588-A2 | Compositions of alkylbenzenes for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | claimed |
| US-5334370-A | X-ray contrast mixtures for diagnostic radiology consisting of iodo alkylbenzene, a polysaccharide salt or a anionic polymers | STERLING WINTHROP INC. (US) | 1994-08-02 | — | — | US | claimed |
| US-5308607-A | FOR USE IN DIAGNOSTIC RADIOLOGY | STERLING WINTHROP INC. (US) | 1994-05-03 | — | — | US | claimed |
| EP-0746339-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING AS (NO) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022995-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING A/S (NO) | 1995-08-31 | — | — | WO | disclosed |
| US-5385721-A | X-ray radiology and computer tomography; uniform coating of the soft tissues; medical diagnosis | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0609589-A2 | Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | disclosed |
| EP-0609588-A2 | Compositions of alkylbenzenes for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | disclosed |
| US-5334370-A | X-ray contrast mixtures for diagnostic radiology consisting of iodo alkylbenzene, a polysaccharide salt or a anionic polymers | STERLING WINTHROP INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5308607-A | FOR USE IN DIAGNOSTIC RADIOLOGY | STERLING WINTHROP INC. (US) | 1994-05-03 | — | — | US | disclosed |