Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 10/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 8/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318657 | 0.92 | LMNA (0.35) | PTGDR2THRBHIF1APLA2G7SMN1; SMN2 | |
| SCHEMBL8322789 | 0.87 | MEN1 (0.41) | PTGDR2THRBAKR1B1THRAHIF1A | |
| SCHEMBL8318204 | 0.84 | SMN1; SMN2 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL9015972 | 0.84 | FFAR1 (0.32) | THRBTHRAHIF1APLA2G7FFAR1 | |
| SCHEMBL8318409 | 0.84 | LMNA (0.36) | PTGDR2THRBHIF1APLA2G7TLR7 | |
| SCHEMBL8321468 | 0.81 | MAPK1 (0.33) | THRBTHRAPLA2G7TLR7 | |
| SCHEMBL8319192 | 0.81 | BCAT2 (0.36) | PLA2G7 | |
| SCHEMBL8320812 | 0.79 | MEN1 (0.38) | PLA2G7SMN1; SMN2 | |
| SCHEMBL8326574 | 0.79 | GRIN1 (0.37) | PTGDR2PLA2G7SMN1; SMN2 | |
| SCHEMBL8316048 | 0.78 | SMN1; SMN2 (0.47) | FFAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519133-A | CYCLIZATION, ALKYLATION | AMERICAN CYANAMID CO. (US) | 1996-05-21 | — | — | US | disclosed |