Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046011 | 0.72 | MAPT (0.48) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2103221 | 0.72 | PGR (0.35) | MAPTALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL182877 | 0.72 | MAPT (0.52) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL489425 | 0.71 | MAPT (0.47) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL31479884 | 0.71 | KAT2B (0.48) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL24322415 | 0.71 | MAPT (0.56) | MAPTALDH1A1HTTSMN1; SMN2KDM4E | |
| Iodide SCHEMBL29028129 | 0.70 | MAPT (0.50) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL6702357 | 0.70 | MAPT (0.50) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL17710400 | 0.70 | MAPT (0.50) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL17710427 | 0.69 | MAPT (0.46) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |