SCHEMBL182877

SCHEMBL182877

CC(C)CNc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
IDO1 P14902 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 3/20 0.44
CYP3A4 P08684 2/20 0.44
ALOX15 P16050 2/20 0.44
ALOX12 P18054 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
ESR1 P03372 1/20 0.43
ACP1 P24666 1/20 0.43
DNM1 Q05193 1/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17710400 0.98 MAPT (0.50) MAPTALDH1A1TDP1IDO1HTT
Ammonia Solution, Strong SCHEMBL6702357 0.98 MAPT (0.50) MAPTALDH1A1TDP1IDO1HTT
Iodide SCHEMBL29028129 0.98 MAPT (0.50) MAPTALDH1A1TDP1IDO1HTT
SCHEMBL809618 0.91 ALDH1A1 (0.56) MAPTALDH1A1TDP1IDO1HTT
SCHEMBL146034 0.87 IDO1 (0.45) MAPTALDH1A1TDP1IDO1SMN1; SMN2
SCHEMBL7163224 0.87 FNTA (0.58) MAPTALDH1A1IDO1SMN1; SMN2ACP1
SCHEMBL7386242 0.82 MGLL (0.46) ACP1ADRB2ADRB1ADRB3
SCHEMBL10359189 0.81 MAPT (0.48) MAPTALDH1A1TDP1HTTSMN1; SMN2
SCHEMBL11848304 0.81 MAPT (0.48) MAPTALDH1A1TDP1HTTSMN1; SMN2
SCHEMBL16197831 0.81 MAPT (0.58) MAPTALDH1A1TDP1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 636 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322132-B N-substituted indole compound and synthesis method thereof 陕西科技大学 2024-05-28 CN claimed
CN-115322132-A N-substituted indole compound and synthetic method thereof 陕西科技大学 2022-11-11 CN claimed
CN-110590844-A Preparation method for synthesizing tenofovir alafenamide by two-step method 江西农业大学 2019-12-20 CN claimed
CN-110551153-A Preparation method for synthesizing tenofovir alafenamide by three-step method UNIV JIANGXI AGRICULTURAL 2019-12-10 CN claimed
CN-108727695-A A kind of automobile cover plate composite material 宁波帅特龙集团有限公司 2018-11-02 CN claimed
CN-107445846-A The technique of isobutyl-aniline between a kind of synthesis 江苏广域化学有限公司 2017-12-08 CN claimed
US-9527042-B2 Separation membrane for water treatment and production method for same TORAY INDUSTRIES, INC. (JP) 2016-12-27 US claimed
EP-2313481-A2 PRODUCTION PROCESS OF UNLEADED HIGH OCTANE NUMBER GASOLINE, AND SO OBTAINED GASOLINES CHIMEC S.P.A. (IT) 2011-04-27 EP claimed
WO-2010001341-A2 PRODUCTION PROCESS OF UNLEADED HIGH OCTANE NUMBER GASOLINE, AND SO OBTAINED GASOLINES CHIMEC S.P.A. (IT) 2010-01-07 WO claimed
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US claimed
EP-1971668-A1 LEAD-FREE AVIATION FUEL Total France (FR) 2008-09-24 EP claimed
WO-2007074226-A1 LEAD-FREE AVIATION FUEL TOTAL FRANCE (FR) 2007-07-05 WO claimed
EP-0979264-B1 The use of a lubricant in a two-stroke mtorcycle CASTROL LTD (GB) 2005-01-05 EP claimed
CN-1405631-A Self-sensitizing type super-branched polyimide photo-sensitive material and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2003-03-26 CN claimed
US-20020049316-A1 Protease inhibitors HALBERT STACIE MARIE (US) 2002-04-25 US claimed
US-6281173-B1 MINERAL OIL FROM A NAPHTHENIC CRUDE SOURCE HAVING A VISCOSITY OF 100 DEGREES C. OF LESS THAN 4 CST AND A POUR POINT BELOW -30 DEGREES C., TO IMPROVE DETERGENCY, REDUCE BLOCKING OF EXHAUSTS AND CATALYSTS, AND PRODUCE LOW LEVELS OF SMOKE CASTROL LIMITED (GB) 2001-08-28 US claimed
CN-1261276-A Protease inhibitors SMITHKLINE BEECHAM CORP (US) 2000-07-26 CN claimed
US-5026912-A High selectivity to ortho-alkylated amines AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-06-25 US claimed
EP-4678620-A1 FAST-CURING ANCHOR SYSTEM WITH OPTIMIZED HARDENER DISTRIBUTION Hilti Aktiengesellschaft (LI) 2026-01-14 EP disclosed
US-3992405-A ESPECIALLY FOR DYEING POLYACRYLIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049316-A1 Protease inhibitors CTSK, CTSZ, CTSG MAPT 796/4885ALDH1A1 2831/4885TDP1 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.