SCHEMBL901604

SCHEMBL901604

CC(C)c1cccc(C(C)C)c1NC(=O)C(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
GAA P10253 1/20 0.53
LPAR1 Q92633 1/20 0.51
MEN1 O00255 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
NLRP3 Q96P20 2/20 0.48
SOAT2 O75908 1/20 0.47
SOAT1 P35610 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9754297 0.84 KMT2A (0.57) KMT2ALMNASMN1; SMN2LPAR1MEN1
SCHEMBL9470522 0.84 SMN1; SMN2 (0.60) KMT2ALMNASMN1; SMN2GAALPAR1
SCHEMBL19422608 0.83 SMN1; SMN2 (0.55) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL31155743 0.82 KMT2A (0.58) KMT2ALMNASMN1; SMN2LPAR1MEN1
SCHEMBL9678499 0.80 SMN1; SMN2 (0.53) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL462304 0.80 LPAR1 (0.66) KMT2ALMNASMN1; SMN2LPAR1MEN1
SCHEMBL6429941 0.80 KMT2A (0.65) KMT2ALMNASMN1; SMN2LPAR1MEN1
SCHEMBL8845511 0.79 KMT2A (0.68) KMT2ALMNASMN1; SMN2LPAR1MEN1
SCHEMBL1726368 0.79 KMT2A (0.62) KMT2ALMNASMN1; SMN2LPAR1MEN1
SCHEMBL30525296 0.79 CETP (0.59) KMT2ALMNAMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795315-B2 Group 5 metal complexes for producing amine-functionalized polyolefins THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-10-24 US disclosed
CN-115207426-A Boron-based negative electrode electrolyte and organic flow battery comprising same 香港科技大学 2022-10-18 CN disclosed
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed
US-9079869-B2 Chiral disulfonimides STUDIENGESELLSCHAFT KOHLE MBH (DE) 2015-07-14 US disclosed
WO-2012040853-A1 GROUP 5 METAL COMPLEXES USEFUL FOR AMINE FUNCTIONALIZATION AND SYNTHETIC PROCESS FOR MANUFACTURE THEREOF THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2012-04-05 WO disclosed
US-20110313150-A1 CHIRAL DISULFONIMIDES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313150-A1 CHIRAL DISULFONIMIDES STS, SUDS3, SF1 KMT2A 3397/4885LMNA 1831/4885SMN1; SMN2 1930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.