Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901604 | 0.84 | KMT2A (0.57) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL28634783 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL9754297 | 0.79 | KMT2A (0.57) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL462304 | 0.79 | LPAR1 (0.66) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL6429941 | 0.79 | KMT2A (0.65) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL19422608 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL1726368 | 0.77 | KMT2A (0.62) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL8845511 | 0.77 | KMT2A (0.68) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL15243085 | 0.77 | KMT2A (0.50) | SMN1; SMN2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL31155743 | 0.77 | KMT2A (0.58) | SMN1; SMN2KMT2ALMNAMEN1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219859-A | Chloesterol acyltransferase inhibitors; antilipemic agents; antidiabetic agents; atherosclerosis | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1993-06-15 | — | — | US | disclosed |