Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | CTSC | P53634 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26371896 | 1.00 | MEN1 (0.57) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL30180690 | 0.86 | MEN1 (0.70) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL475267 | 0.86 | MEN1 (0.70) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL1195735 | 0.86 | MEN1 (0.70) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL122907 | 0.86 | MEN1 (0.70) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL19161138 | 0.86 | MEN1 (0.70) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL29398306 | 0.85 | MEN1 (0.68) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL378071 | 0.85 | MEN1 (0.68) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL378072 | 0.85 | MEN1 (0.68) | MEN1KMT2AHCRTR1CTSCMAPT | |
| Tryptophan Methyl Ester SCHEMBL475266 | 0.85 | MEN1 (0.68) | MEN1KMT2AHCRTR1CTSCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508432-A | TREATING GASTROINTESTINAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO WELLCOME INC. (US) | 1996-04-16 | — | — | US | disclosed |
| US-5380872-A | Appetite suppresant, gall bladder disorders, CNS disorders | GLAXO INC. (US) | 1995-01-10 | — | — | US | disclosed |