Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | TACR1 | P25103 | 8/20 | 0.57 |
| ▸ | TACR3 | P29371 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020291 | 1.00 | CTSL (0.59) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL3020294 | 1.00 | CTSL (0.59) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL16694906 | 0.90 | TACR1 (0.56) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL10625966 | 0.90 | TACR1 (0.52) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL10625499 | 0.89 | TACR1 (0.52) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL10625491 | 0.89 | TACR1 (0.52) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL8651829 | 0.87 | CTSL (0.58) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL10746226 | 0.86 | TACR1 (0.48) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL8650748 | 0.86 | CTSL (0.57) | CTSLCTSSCTSKTACR1TACR3 | |
| SCHEMBL9016095 | 0.85 | TACR1 (0.74) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508432-A | TREATING GASTROINTESTINAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO WELLCOME INC. (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1994015917-A1 | ALPHA-METHYL-(R)-TRYPTOPHYL-ARYLCYCLOALKYLALKYLAMIDES AS LIGANDS FOR GASTRIN RECEPTORS | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J.) (FR) | 1994-07-21 | — | — | WO | disclosed |