Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020294 | 0.86 | CTSL (0.59) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL3020291 | 0.86 | CTSL (0.59) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL9016089 | 0.86 | CTSL (0.59) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL8651829 | 0.85 | CTSL (0.58) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL9270557 | 0.82 | CTSL (0.55) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL8650822 | 0.81 | CTSL (0.62) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL2193454 | 0.81 | CTSL (0.55) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL16694906 | 0.80 | TACR1 (0.56) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL4806740 | 0.80 | TACR1 (0.52) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL1003555 | 0.78 | ACE (0.77) | CTSLCTSSCTSKTACR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632052-B1 | Endothelin antagonistic peptides | BANYU PHARMA CO LTD (JP) | 1998-09-30 | — | — | EP | disclosed |