Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036762 | 0.77 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL3550004 | 0.74 | POLB (0.50) | POLBOPRM1TSHRATM | |
| SCHEMBL29191658 | 0.73 | OPRM1 (0.42) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL2912108 | 0.68 | CRBN (0.36) | POLB | |
| SCHEMBL3545508 | 0.68 | ATM (0.33) | ELANETSHRATM | |
| Hydrochloric Acid SCHEMBL3219393 | 0.67 | KDM4E (0.37) | POLB | |
| SCHEMBL27722464 | 0.67 | OPRM1 (0.43) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL22931287 | 0.66 | — | — | |
| SCHEMBL20814181 | 0.66 | OPRM1 (0.38) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL30997917 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500426-A | ADMINISTERED TO IMPROVE GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |