Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | CASP1 | P29466 | 1/20 | 0.73 |
| ▸ | CASP7 | P55210 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.62 |
| ▸ | NQO2 | P16083 | 3/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584432 | 1.00 | HIF1A (0.78) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL9016238 | 1.00 | HIF1A (0.78) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL29583263 | 0.87 | HIF1A (0.81) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL9016262 | 0.87 | HIF1A (0.81) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL30200254 | 0.87 | HIF1A (1.00) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL29929793 | 0.87 | HIF1A (1.00) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL9016260 | 0.87 | HIF1A (0.81) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| Yangonin SCHEMBL1393965 | 0.84 | ALDH1A1 (1.00) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| Yangonin SCHEMBL5584097 | 0.84 | ALDH1A1 (1.00) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL18104327 | 0.84 | HIF1A (0.67) | HIF1AALDH1A1TP53HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349548-A1 | P21-ACTIVATED KINASE INHIBITOR | BIOSYSTEM CONSULTING LIMITED COMPANY (JP) | 2017-12-07 | — | — | US | claimed |
| US-20170349548-A1 | P21-ACTIVATED KINASE INHIBITOR | BIOSYSTEM CONSULTING LIMITED COMPANY (JP) | 2017-12-07 | — | — | US | disclosed |
| US-5585386-A | MIXTURES FOR APPLICATION TO SKIN OR SCALP | L'OREAL (FR) | 1996-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349548-A1 | P21-ACTIVATED KINASE INHIBITOR | HIPK1, CDKN1A, HIPK2 | HIF1A 2205/4885ALDH1A1 2838/4885TP53 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.