Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | CASP7 | P55210 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 4/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016262 | 1.00 | HIF1A (0.81) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29583263 | 1.00 | HIF1A (0.81) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29929793 | 0.89 | HIF1A (1.00) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30200254 | 0.89 | HIF1A (1.00) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19665470 | 0.89 | HIF1A (0.80) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19665468 | 0.89 | HIF1A (0.80) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23242770 | 0.88 | ALDH1A1 (0.69) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23242768 | 0.88 | ALDH1A1 (0.69) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29584432 | 0.87 | HIF1A (0.78) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9016241 | 0.87 | HIF1A (0.78) | HIF1AHPGDMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585386-A | MIXTURES FOR APPLICATION TO SKIN OR SCALP | L'OREAL (FR) | 1996-12-17 | — | — | US | disclosed |