Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016221 | 0.93 | KCNH2 (0.57) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016252 | 0.93 | KCNH2 (0.61) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016222 | 0.93 | KCNH2 (0.61) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016210 | 0.91 | KCNH2 (0.59) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016229 | 0.90 | HTR2B (0.60) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016230 | 0.88 | KCNH2 (0.56) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016234 | 0.87 | HTR2B (0.57) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016250 | 0.87 | KCNH2 (0.59) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016232 | 0.87 | KCNH2 (0.54) | KCNH2ADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL9016244 | 0.87 | ADRB2 (0.63) | KCNH2ADRB2ADRB1HTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482964-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |