Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465923 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2C9EPHX1TP53PTPN1 | |
| SCHEMBL6466723 | 0.81 | CYP2C9 (0.57) | SMN1; SMN2TSHRCYP2C9EPHX1TP53 | |
| SCHEMBL714625 | 0.80 | EPHX1 (0.77) | SMN1; SMN2KDM4ETSHRCYP2C9EPHX1 | |
| SCHEMBL5186630 | 0.78 | ALDH1A1 (0.75) | SMN1; SMN2TSHRCYP2C9CA12CA1 | |
| SCHEMBL969258 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2TSHRCYP2C9EPHX1TP53 | |
| SCHEMBL6033584 | 0.77 | TP53 (0.75) | SMN1; SMN2KDM4ETSHRCYP2C9EPHX1 | |
| SCHEMBL5313231 | 0.76 | KDM4E (0.61) | KDM4EPOLBTSHRRECQLEPHX2 | |
| SCHEMBL11543125 | 0.76 | TP53 (0.50) | SMN1; SMN2KDM4EPOLBTSHRRECQL | |
| SCHEMBL970225 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBEPHX1TP53PTPN1 | |
| SCHEMBL26965437 | 0.75 | KMT2A (0.68) | KDM4EPOLBTSHRRECQLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748315-A1 | USE OF IMIDAZOLE DERIVATIVES FOR TREATING DISORDERS INVOLVING ANGIOTENSIN RECEPTORS AT 1? AND AT 2?, CERTAIN SUCH PRODUCTS, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1996-12-18 | — | — | EP | disclosed |