Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448931 | 0.82 | KMT2A (0.62) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9448933 | 0.82 | KMT2A (0.62) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL2596959 | 0.80 | KMT2A (0.66) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9016492 | 0.80 | CYP1A2 (0.53) | GAAALDH1A1LMNACYP1A2 | |
| SCHEMBL9011582 | 0.79 | KMT2A (0.63) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL10773171 | 0.79 | KMT2A (0.58) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL7043903 | 0.79 | KMT2A (0.58) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL18901910 | 0.78 | CYP1A2 (0.45) | GAAKMT2AMEN1LMNATSHR | |
| SCHEMBL19718025 | 0.76 | KMT2A (0.55) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL7638396 | 0.74 | GAA (0.47) | GAAKMT2AMEN1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |