SCHEMBL2596959

SCHEMBL2596959

COC(=O)C(C=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
MEN1 O00255 2/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.42
CYP1A2 P05177 1/20 0.42
SLC6A3 Q01959 4/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011582 0.98 KMT2A (0.63) KMT2AMEN1PTGS1PTGS2ALDH1A1
SCHEMBL9448931 0.86 KMT2A (0.62) KMT2AMEN1PTGS1PTGS2ALDH1A1
SCHEMBL9448933 0.86 KMT2A (0.62) KMT2AMEN1PTGS1PTGS2ALDH1A1
SCHEMBL10773171 0.83 KMT2A (0.58) KMT2AMEN1PTGS1PTGS2ALDH1A1
SCHEMBL7043903 0.83 KMT2A (0.58) KMT2AMEN1PTGS1PTGS2ALDH1A1
SCHEMBL23409168 0.81 RAB9A (0.46) KMT2AMEN1ALDH1A1
SCHEMBL1516027 0.81 MMP8 (0.53) KMT2AMEN1LMNATSHR
SCHEMBL31726783 0.81 KMT2A (0.43) KMT2AMEN1ALDH1A1LMNATSHR
SCHEMBL27964745 0.81 L3MBTL1 (0.47) KMT2ASLC6A3SLC6A2SLC6A4
SCHEMBL15020603 0.81 KMT2A (0.47) KMT2AMEN1PTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396160-B Method for preparing tropine acid and method for preparing atropine sulfate by using tropine acid 烟台万润药业有限公司 2023-08-22 CN claimed
CN-115754042-B Method for detecting impurity alpha-formylphenyl methyl acetate in ipratropium bromide 石家庄四药有限公司 2023-06-09 CN claimed
CN-115754042-A Method for detecting impurity alpha-formyl methyl phenylacetate in ipratropium bromide 石家庄四药有限公司 2023-03-07 CN claimed
CN-105985241-A Inhibition effect of [alpha]-substituted phenyl acetate compounds on [alpha]-glycosidase and application of the compounds 邵阳学院 2016-10-05 CN claimed
US-20260040820-A1 PHENANTHROLINE COMPOUND, AND ORGANIC THIN FILM AND ORGANIC SEMICONDUCTOR ELEMENT USING SAME NIPPON CATALYTIC CHEM IND (JP) 2026-02-05 US disclosed
US-20260001886-A1 ENPP1 INHIBITORS I RE VENTURES I LLC (US) 2026-01-01 US disclosed
WO-2025233863-A1 ENPP1 INHIBITORS RE VENTURES I, LLC (US) 2025-11-13 WO disclosed
EP-4622958-A1 SYNTHESIS OF PYRROLO[3,4-C]PYRROLES Novo Nordisk Health Care AG (CH) 2025-10-01 EP disclosed
EP-4619376-A2 CYCLIC DESIGNER SCAFFOLDS FOR THE COVALENT TARGETING OF PROTEINS VIA MICHAEL ADDITION Protenic Fejleszto Es Szolgaltato Kft. (HU) 2025-09-24 EP disclosed
CN-115572290-B Method for synthesizing ipratropium bromide by one-pot method 河北仁合益康药业有限公司 2024-11-26 CN disclosed
WO-2024112764-A1 SYNTHESIS OF PYRROLO[3,4-C]PYRROLES NOVO NORDISK HEALTH CARE AG (CH) 2024-05-30 WO disclosed
WO-2024105420-A2 CYCLIC DESIGNER SCAFFOLDS FOR THE COVALENT TARGETING OF PROTEINS VIA MICHAEL ADDITION Természettudományi Kutatóközpont (HU) 2024-05-23 WO disclosed
CN-1144475-A Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds UNILEVER PLC (NL) 1997-03-05 CN disclosed
US-5574153-A BACTERICIDES ACS DOBFAR S.P.A. (IT) 1996-11-12 US disclosed
EP-0638574-A1 Oxime derivatives of cephalosporanic structure and compounds for their preparation ACS DOBFAR S.p.A. (IT) 1995-02-15 EP disclosed
WO-1994006737-A1 PROCESS FOR PREPARING FELBAMATE, 2-PHENYL-1,3-PROPANEDIOL AND INTERMEDIATES SCHERING CORPORATION (US) 1994-03-31 WO disclosed
EP-0588652-A1 Process for the preparation of 2-aryl-1,3-propanediols GANES CHEMICALS INC. (US) 1994-03-23 EP disclosed
US-4997955-A From aldehyde BASF AKTIENGESELLSCHAFT (DE) 1991-03-05 US disclosed
EP-0132987-B1 IMPROVEMENTS IN OR RELATING TO DEESTERIFICATION TO ACIDS ELI LILLY AND COMPANY (US) 1987-09-16 EP disclosed
EP-0132987-A1 Improvements in or relating to deesterification to acids ELI LILLY AND COMPANY (US) 1985-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260040820-A1 PHENANTHROLINE COMPOUND, AND ORGANIC THIN FILM AND ORGANIC SEMICONDUCTOR ELEMENT USING SAME AHR, PAH, PROX1 KMT2A 1112/4885MEN1 1870/4885PTGS1 2871/4885
US-20260001886-A1 ENPP1 INHIBITORS I ENPP1, ENPP2, ENPP3 KMT2A 4484/4885MEN1 290/4885PTGS1 483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.