SCHEMBL9016492

SCHEMBL9016492

O=C(O)C(C=NO)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.53
LMNA P02545 4/20 0.50
MAPK1 P28482 1/20 0.50
SRC P12931 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.40
GAA P10253 2/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18901910 0.82 CYP1A2 (0.45) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL18526631 0.82 CYP1A2 (0.45) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL9016427 0.80 GAA (0.55) CYP1A2LMNAGAAALDH1A1
SCHEMBL25404016 0.78 CYP1A2 (0.61) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL9016418 0.77 CYP1A2 (0.47) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL9016539 0.76 CYP1A2 (0.46) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL1302046 0.76 CYP1A2 (0.59) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL25121338 0.76 CYP1A2 (0.59) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL12833352 0.74 CYP1A2 (0.57) CYP1A2LMNAMAPK1SRCCYP2D6
SCHEMBL10402902 0.74 CYP1A2 (0.57) CYP1A2LMNAMAPK1SRCCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117185954-A Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof 江西天宇化工有限公司 2023-12-08 CN claimed
CN-112851546-B Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof 江西天宇化工有限公司 2023-10-03 CN claimed
CN-112851546-A Preparation method of (E) -2-methyl-alpha-methoxyimino methyl phenylacetate and intermediate thereof 江西天宇化工有限公司 2021-05-28 CN claimed
CN-119638597-B Synthesis method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester 内蒙古诚信永安化工有限公司 2025-06-10 CN disclosed
CN-119638597-A Synthesis method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester 内蒙古诚信永安化工有限公司 2025-03-18 CN disclosed
CN-220835569-U Device for continuously synthesizing (E) -2-methyl-alpha-oxyiminophenylacetic acid 湖北省祥珈科技有限公司 2024-04-26 CN disclosed
CN-117185954-A Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof 江西天宇化工有限公司 2023-12-08 CN disclosed
CN-117185954-A Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof 江西天宇化工有限公司 2023-12-08 CN disclosed
CN-112851546-B Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof 江西天宇化工有限公司 2023-10-03 CN disclosed
CN-112851546-B Preparation method of (E) -2-methyl-alpha-methoxyiminophenylacetic acid methyl ester and intermediate thereof 江西天宇化工有限公司 2023-10-03 CN disclosed
CN-112851546-A Preparation method of (E) -2-methyl-alpha-methoxyimino methyl phenylacetate and intermediate thereof 江西天宇化工有限公司 2021-05-28 CN disclosed
US-5574153-A BACTERICIDES ACS DOBFAR S.P.A. (IT) 1996-11-12 US disclosed
EP-0638574-A1 Oxime derivatives of cephalosporanic structure and compounds for their preparation ACS DOBFAR S.p.A. (IT) 1995-02-15 EP disclosed